ADCK2

Across TCGA patient cohorts, ADCK2 mutation is significantly associated with the RNA expression of many other genes, with 741 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADCK2-associated genes across cancer lineages are RAB28P2, MIR6839, and RPS29P32. Each is linked with ADCK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADCK2-to-partner and partner-to-ADCK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAB28P2 grouped by ADCK2-low versus ADCK2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCK2→partner) and Y-score (partner→ADCK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RAB28P2 →	+0.040	+4.039	.001	.009	3	3
UCEC	MIR6839 →	+0.223	+2.714	<.001	.001	3	2
UCEC	RPS29P32 →	+0.371	+2.377	<.001	.002	3	2
HNSC	MIR519A1 →	+0.525	+5.822	<.001	.003	3	2
BRCA	GAPDHP34 →	+0.083	+6.064	<.001	.002	3	2
COAD	RNU6-136P →	+0.513	+4.221	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 741 associations by consensus.

RAB28P2 by ADCK2 expression — SKCM

Explore this box plot interactively →