ADCK1

Across TCGA pan-cancer cohorts, ADCK1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ADCK1 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ADCK1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ADCK1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

HNSC, PDAC, and CCRCC are the cancer types where ADCK1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.310	1.000	.022	30	view →
PDAC	DFS	Tertile	II,III,IV	0.901	0.665	.035	4	view →
CCRCC	OS	Median	II,III,IV	1.000	0.449	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ADCK1–HNSC (DFS)

Open the HNSC breakdown →