Across TCGA cell cohorts, ADAT3 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADAT3-associated genes across cancer lineages are KRT71, PCARE, and HTR3D. Each is linked with ADAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAT3-to-partner and partner-to-ADAT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAT3→partner) and Y-score (partner→ADAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRT71 →	+0.009	+4.643	<.001	.005	3	2
BLOOD_Lymphoma	PCARE →	+0.038	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	HTR3D →	+0.015	+5.247	<.001	.001	3	1
BLOOD_Leukemia	SLC32A1 →	+0.569	+4.223	<.001	.001	3	1
BLOOD_Leukemia	APOL5 →	+0.010	+3.475	.007	.006	3	1
BLOOD_Leukemia	CSH1 →	+0.046	+3.339	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

ADAT3 survival (RNA) · tumor vs normal (RNA) · all ADAT3 data types