Across TCGA patient cohorts, ADARB2 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADARB2-associated genes across cancer lineages are FASN, MIG-6, and Caspase-7-cleavedD198. Each is linked with ADARB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADARB2-to-partner and partner-to-ADARB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADARB2→partner) and Y-score (partner→ADARB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FASN →	+0.459	+2.815	.032	.036	3	3
SKCM	MIG-6 →	+0.129	+1.695	.034	.013	3	3
COAD	Caspase-7-cleavedD198 →	+1.378	+2.815	.001	.036	3	3
LUSC	Dvl3 →	-0.244	-3.000	.002	.033	3	2
SKCM	AMPK_alpha →	+0.220	+3.807	<.001	<.001	3	2
SKCM	TAZ →	+0.139	+2.472	.022	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

ADARB2 survival (RNA) · tumor vs normal (RNA) · all ADARB2 data types