Across TCGA cell cohorts, ADARB2 mutation is significantly associated with the RNA expression of many other genes, with 382 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADARB2-associated genes across cancer lineages are CCDC134, PANK3, and MAGEB4. Each is linked with ADARB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADARB2-to-partner and partner-to-ADARB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADARB2→partner) and Y-score (partner→ADARB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC134 →	+0.678	+2.502	.003	.005	3	2
LARGE_INTESTINE	PANK3 →	+0.542	+3.169	.003	.005	3	2
LARGE_INTESTINE	MAGEB4 →	+0.007	+2.678	.001	.005	3	2
LARGE_INTESTINE	KDM3B →	+0.406	+3.067	.008	.009	3	2
LARGE_INTESTINE	WNT3A →	+0.198	+2.584	.001	.008	3	2
LARGE_INTESTINE	TATDN2 →	+0.477	+2.502	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 382 associations by consensus.

Exploration

ADARB2 survival (RNA) · tumor vs normal (RNA) · all ADARB2 data types