ADARB2-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ADARB2-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ADARB2-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ADARB2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ADARB2-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and THYM show a favorable association.

BRCA, READ, and ACC are the cancer types where ADARB2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.4150.647<.00183view →
READDFSMedianAll0.8070.371.00476view →
ACCOSTertileAll0.6470.905.00163view →
SKCMDFSTertileIII,IV0.2350.627<.00157view →
LUSCDFSQuartileIII,IV0.4270.742.00138view →
UCECOSTertileAll0.5500.736<.00136view →
THYMDFSTertileAll1.0000.740.00232view →
UVMOSTertileAll0.2720.721.00127view →
UCSDFSTertileIV0.3600.981.02424view →
KIRCOSTertileAll0.5030.670.00324view →
BLCADFSTertileIV0.6660.413.00521view →
LIHCDFSTertileAll0.2880.447.02418view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration