Across TCGA patient cohorts, ADARB1 mutation is significantly associated with the total protein of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADARB1-associated genes across cancer lineages are MEK1, eEF2, and ATM. Each is linked with ADARB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADARB1-to-partner and partner-to-ADARB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADARB1→partner) and Y-score (partner→ADARB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.565	+3.321	<.001	<.001	3	3
UCEC	eEF2 →	+0.304	+1.643	.006	.003	3	3
UCEC	ATM →	-0.554	-2.169	<.001	<.001	3	3
COAD	EGFR_pY1068 →	-0.398	-3.157	.009	.018	3	2
COAD	NF2 →	+0.190	+2.178	.037	.035	3	2
COAD	PDCD4 →	-0.540	-3.313	.006	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

Exploration

ADARB1 survival (RNA) · tumor vs normal (RNA) · all ADARB1 data types