Across TCGA cell cohorts, ADAP2 mutation is significantly associated with the mutation status of many other genes, with 3,115 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADAP2-associated genes across cancer lineages are SUN1, PATZ1, and TNRC6B. Each is linked with ADAP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADAP2-to-partner and partner-to-ADAP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAP2→partner) and Y-score (partner→ADAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	SUN1 →	+4.392	+4.954	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	PATZ1 →	+5.392	+5.392	.004	.004	1	3
BLOOD_Leukemia	TNRC6B →	+3.157	+4.665	.003	.003	1	3
UPPER_AERODIGESTIVE_TRACT	IRAK2 →	+5.392	+5.392	.004	.004	1	3
BLOOD_Leukemia	SOGA1 →	+3.479	+4.932	.002	.002	1	3
BLOOD_Leukemia	AAAS →	+4.894	+4.894	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,115 associations by consensus.

Exploration

ADAP2 survival (RNA) · tumor vs normal (RNA) · all ADAP2 data types