Across TCGA patient cohorts, ADAMTSL5 mutation is significantly associated with the RNA expression of many other genes, with 308 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAMTSL5-associated genes across cancer lineages are RN7SKP261, RNU6-1301P, and CPSF7. Each is linked with ADAMTSL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAMTSL5-to-partner and partner-to-ADAMTSL5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTSL5→partner) and Y-score (partner→ADAMTSL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP261 →	+0.357	+3.484	<.001	.006	3	2
UCEC	RNU6-1301P →	+0.376	+2.078	.009	.008	3	2
UCEC	CPSF7 →	+0.456	+2.617	.003	.006	3	1
UCEC	CC2D1B →	+0.345	+2.595	.002	.006	3	1
UCEC	ABHD3 →	+0.804	+3.343	.001	.005	3	1
UCEC	RNF166 →	+0.450	+2.606	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 308 associations by consensus.

Exploration

ADAMTSL5 survival (RNA) · tumor vs normal (RNA) · all ADAMTSL5 data types