ADAMTSL4

Across TCGA patient cohorts, ADAMTSL4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,602 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADAMTSL4-associated proteins across cancer lineages are ALOX5, PPP1R18_S224, and TOMM22. Each is linked with ADAMTSL4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADAMTSL4-to-partner and partner-to-ADAMTSL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTSL4 versus ALOX5 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTSL4→partner) and Y-score (partner→ADAMTSL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ALOX5 →	+0.791	+0.736	<.001	<.001	3	6
LSCC	PPP1R18_S224 →	+0.751	+0.861	<.001	<.001	3	5
LSCC	TOMM22 →	-0.331	-0.697	<.001	<.001	3	5
OV	VIM_S22 →	+0.858	+0.679	<.001	<.001	3	5
COAD	CTSL →	+0.404	+0.701	.003	<.001	3	5
BRCA	DOCK11 →	+0.314	+0.626	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,602 associations by consensus.

ADAMTSL4 vs ALOX5 — GBM

Explore this scatter interactively →