ADAMTSL4-AS2

Across TCGA pan-cancer cohorts, ADAMTSL4-AS2 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ADAMTSL4-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ADAMTSL4-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ADAMTSL4-AS2 expression acts as an unfavorable survival marker, although some lineages such as UCS and BLCA show a favorable association.

KIRC, UCS, and UVM are the cancer types where ADAMTSL4-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.545	0.693	<.001	136	view →
UCS	DFS	Median	IV	0.952	0.367	.001	60	view →
UVM	DFS	Quartile	II,III,IV	0.264	0.718	.005	42	view →
LGG	DFS	Median	All	0.660	0.810	<.001	39	view →
BLCA	DFS	Tertile	All	0.479	0.263	.001	38	view →
OV	OS	Median	III,IV	0.802	0.866	.013	32	view →
UCEC	DFS	Tertile	All	0.763	0.871	.002	32	view →
SKCM	OS	Tertile	II,III,IV	0.501	0.278	.004	29	view →
LUAD	DFS	Median	IV	0.507	0.854	.003	19	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	18	view →
MESO	DFS	Quartile	III,IV	0.491	0.238	.001	17	view →
PRAD	DFS	Tertile	All	0.839	0.936	.002	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ADAMTSL4-AS2–KIRC (DFS)

Open the KIRC breakdown →