ADAMTSL3

Across TCGA patient cohorts, ADAMTSL3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,828 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ADAMTSL3-associated genes across cancer lineages are SGCA, INMT, and IGFBP7. Each is linked with ADAMTSL3 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADAMTSL3-to-partner and partner-to-ADAMTSL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTSL3 versus SGCA in PDAC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTSL3→partner) and Y-score (partner→ADAMTSL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SGCA →	+0.759	+0.549	<.001	<.001	3	6
LSCC	INMT →	+1.347	+0.460	<.001	<.001	3	5
UCEC	IGFBP7 →	+0.863	+0.733	.001	<.001	3	5
UCEC	CNRIP1 →	+0.840	+0.557	<.001	.002	3	4
BRCA	SVEP1 →	+0.782	+0.584	.006	<.001	3	4
UCEC	TNXB →	+0.953	+0.399	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,828 associations by consensus.

ADAMTSL3 vs SGCA — PDAC

Explore this scatter interactively →