Across TCGA patient cohorts, ADAMTSL2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,183 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ADAMTSL2-associated genes across cancer lineages are LRRC32, PPFIA2, and CACNA1C. Each is linked with ADAMTSL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADAMTSL2-to-partner and partner-to-ADAMTSL2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTSL2→partner) and Y-score (partner→ADAMTSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LRRC32 →	+1.173	+0.735	<.001	<.001	3	6
PDAC	PPFIA2 →	+0.881	+0.897	<.001	<.001	3	6
UCEC	CACNA1C →	+1.077	+1.173	<.001	<.001	3	6
CCRCC	HEYL →	+1.044	+0.575	<.001	<.001	3	6
UCEC	AXIN2 →	+1.697	+1.445	<.001	<.001	3	6
BRCA	MSRB3 →	+1.169	+0.716	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,183 associations by consensus.

Exploration

ADAMTSL2 survival (RNA) · tumor vs normal (RNA) · all ADAMTSL2 data types