Across TCGA cell cohorts, ADAMTSL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,461 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ADAMTSL2-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Negative regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with ADAMTSL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADAMTSL2-to-partner and partner-to-ADAMTSL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTSL2→partner) and Y-score (partner→ADAMTSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Establishment of protein localization to organelle →	+0.039	+1.843	.001	.001	3	6
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.094	+2.070	<.001	<.001	3	6
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.093	+1.873	<.001	.002	3	6
LUNG_SCLC	Spliceosomal conformational changes to generate catalytic conformation →	+0.090	+2.254	<.001	<.001	3	5
PANCREAS	Chemical synaptic transmission, postsynaptic →	-0.049	-0.160	.004	.007	3	5
BLOOD_Lymphoma	Regulation of stem cell population maintenance →	+0.036	+0.350	.002	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,461 associations by consensus.

Exploration

ADAMTSL2 survival (RNA) · tumor vs normal (RNA) · all ADAMTSL2 data types