ADAMTSL1

Across TCGA cell cohorts, ADAMTSL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,759 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADAMTSL1-associated GO terms across cancer lineages are Positive regulation of stress fiber assembly, Establishment of epithelial cell apical/basal polarity, and Response to UV. Each is linked with ADAMTSL1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ADAMTSL1-to-partner and partner-to-ADAMTSL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stress fiber assembly grouped by ADAMTSL1-low versus ADAMTSL1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTSL1→partner) and Y-score (partner→ADAMTSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of stress fiber assembly →	+0.158	+1.940	<.001	<.001	3	11
OVARY	Establishment of epithelial cell apical/basal polarity →	+0.161	+1.861	<.001	<.001	3	10
SKIN	Response to UV →	+0.053	+0.823	<.001	.004	3	10
BLOOD_Leukemia	Positive regulation of chromosome organization →	+0.055	+0.108	<.001	.001	3	10
BONE	Positive regulation of cell-substrate junction organization →	+0.166	+1.971	<.001	<.001	3	9
SOFT_TISSUE	Regulation of post-translational protein modification →	+0.043	+1.973	.002	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,759 associations by consensus.

Positive regulation of stress fiber assembly by ADAMTSL1 expression — BONE

Explore this box plot interactively →