ADAMTS9-AS1

Across TCGA pan-cancer cohorts, ADAMTS9-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ADAMTS9-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher ADAMTS9-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ADAMTS9-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and KIRC show a favorable association.

KIRP, BLCA, and KIRC are the cancer types where ADAMTS9-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.799	0.592	<.001	173	view →
BLCA	OS	Median	All	0.337	0.570	<.001	136	view →
KIRC	OS	Tertile	All	0.722	0.516	<.001	76	view →
BRCA	OS	Median	All	0.619	0.525	<.001	65	view →
ACC	DFS	Median	All	0.525	0.782	<.001	51	view →
STAD	DFS	Quartile	All	0.447	0.630	<.001	42	view →
UCEC	OS	Quartile	All	0.860	0.952	.001	36	view →
MESO	DFS	Quartile	All	0.530	0.261	.008	31	view →
LGG	DFS	Quartile	All	0.800	0.934	<.001	30	view →
LUSC	DFS	Tertile	II,III,IV	0.293	0.535	.003	23	view →
LAML	DFS	Tertile	All	0.678	0.449	.007	20	view →
UCS	OS	Median	II,III,IV	0.554	0.254	.015	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ADAMTS9-AS1–KIRP (OS)

Open the KIRP breakdown →