Across TCGA pan-cancer cohorts, ADAMTS7P4 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ADAMTS7P4’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where ADAMTS7P4 RNA is repressed in tumor relative to normal tissue. In most cancer types ADAMTS7P4 is over-expressed in tumor, although a few such as BLCA and UCEC show the opposite, repressed pattern.
BLCA, UCEC, and KICH are the cancer types where ADAMTS7P4 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADAMTS7P4 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.