ADAMTS7

Across TCGA patient cohorts, ADAMTS7 protein abundance is significantly associated with the RNA expression of many other genes, with 10,842 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ADAMTS7-associated genes across cancer lineages are ESM1, ANTXR1, and COL12A1. Each is linked with ADAMTS7 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADAMTS7-to-partner and partner-to-ADAMTS7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS7 versus ESM1 in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS7→partner) and Y-score (partner→ADAMTS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ESM1 →	+1.800	+0.900	<.001	<.001	3	6
BRCA	ANTXR1 →	+1.226	+0.459	<.001	<.001	3	6
LUAD	COL12A1 →	+1.454	+0.576	<.001	<.001	3	6
GBM	LAMA4 →	+1.032	+0.843	<.001	<.001	3	6
LSCC	SGIP1 →	+0.888	+0.443	<.001	<.001	3	5
BRCA	LOXL2 →	+1.246	+0.588	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,842 associations by consensus.

ADAMTS7 vs ESM1 — GBM

Explore this scatter interactively →