ADAMTS7

Across TCGA cell cohorts, ADAMTS7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,921 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ADAMTS7-associated GO terms across cancer lineages are Protein depolymerization, Cell division, and Regulation of intracellular transport. Each is linked with ADAMTS7 in more than 12 cancer types. Because this analysis shows association rather than direction, both ADAMTS7-to-partner and partner-to-ADAMTS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by ADAMTS7-low versus ADAMTS7-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS7→partner) and Y-score (partner→ADAMTS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein depolymerization →	+0.113	+1.745	<.001	.001	3	13
BREAST	Cell division →	+0.090	+1.839	<.001	.001	3	12
STOMACH	Regulation of intracellular transport →	+0.067	+0.777	<.001	.009	3	11
OESOPHAGUS	Locomotory exploration behavior →	+0.325	+1.692	<.001	<.001	3	11
BONE	Regulation of early endosome to late endosome transport →	+0.145	+1.970	<.001	<.001	3	11
CNS	Schwann cell development →	+0.098	+1.238	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,921 associations by consensus.

Protein depolymerization by ADAMTS7 expression — BREAST

Explore this box plot interactively →