ADAMTS18

Across TCGA patient cohorts, ADAMTS18 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,882 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ADAMTS18-associated proteins across cancer lineages are MMP2, COL1A2, and SPARCL1_S59. Each is linked with ADAMTS18 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADAMTS18-to-partner and partner-to-ADAMTS18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS18 versus MMP2 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS18→partner) and Y-score (partner→ADAMTS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MMP2 →	+0.830	+0.731	<.001	<.001	3	7
COAD	COL1A2 →	+0.925	+0.306	<.001	<.001	3	7
BRCA	SPARCL1_S59 →	+1.278	+0.673	<.001	<.001	3	6
BRCA	FERMT2 →	+0.600	+0.545	<.001	<.001	3	6
OV	NID2 →	+0.673	+1.027	<.001	<.001	3	5
COAD	PCOLCE →	+0.787	+0.254	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,882 associations by consensus.

ADAMTS18 vs MMP2 — BRCA

Explore this scatter interactively →