ADAMTS18

Across TCGA patient cohorts, ADAMTS18 protein abundance is significantly associated with the RNA expression of many other genes, with 253 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ADAMTS18-associated genes across cancer lineages are OR52E2, OR2T35, and TMF1P1. Each is linked with ADAMTS18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAMTS18-to-partner and partner-to-ADAMTS18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS18 versus OR52E2 in GBM, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS18→partner) and Y-score (partner→ADAMTS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	OR52E2 →	+0.110	+0.688	.003	.008	3	1
GBM	OR2T35 →	+0.049	+0.688	<.001	.008	3	1
GBM	TMF1P1 →	+0.860	+0.906	<.001	<.001	3	1
GBM	MIR548W →	+1.566	+0.688	.003	.008	3	1
GBM	SELENOTP2 →	+0.293	+0.688	.002	.008	3	1
GBM	RN7SL628P →	+0.613	+0.688	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 253 associations by consensus.

ADAMTS18 vs OR52E2 — GBM

Explore this scatter interactively →