ADAMTS18

Across TCGA cell cohorts, ADAMTS18 RNA expression is significantly associated with the go_rna of many other GO terms, with 762 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ADAMTS18-associated GO terms across cancer lineages are Exit from mitosis, Regulation of TORC1 signaling, and Protein targeting to lysosome. Each is linked with ADAMTS18 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADAMTS18-to-partner and partner-to-ADAMTS18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Exit from mitosis grouped by ADAMTS18-low versus ADAMTS18-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS18→partner) and Y-score (partner→ADAMTS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Exit from mitosis →	+0.082	+1.362	.005	.001	3	5
LUNG_SCLC	Regulation of TORC1 signaling →	+0.052	+1.413	.002	.004	2	6
SOFT_TISSUE	Protein targeting to lysosome →	+0.040	+0.483	.008	.003	3	4
LUNG_SCLC	Centrosome duplication →	+0.072	+1.472	.003	<.001	3	4
BLOOD_Leukemia	Negative regulation of adaptive immune response →	-0.056	-0.242	<.001	.009	3	4
LUNG_SCLC	mRNA destabilization →	+0.050	+1.703	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 762 associations by consensus.

Exit from mitosis by ADAMTS18 expression — LUNG_SCLC

Explore this box plot interactively →