ADAMTS13

Across TCGA patient cohorts, ADAMTS13 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,831 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADAMTS13-associated proteins across cancer lineages are SEC11C, SH3KBP1, and SLC38A1_S52. Each is linked with ADAMTS13 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADAMTS13-to-partner and partner-to-ADAMTS13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS13 versus SEC11C in LSCC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS13→partner) and Y-score (partner→ADAMTS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SEC11C →	-1.005	-0.514	<.001	.001	3	3
GBM	SH3KBP1 →	-0.374	-0.512	<.001	<.001	3	3
UCEC	SLC38A1_S52 →	-1.091	-0.698	<.001	<.001	3	3
LSCC	STOML2 →	+0.391	+0.451	<.001	<.001	3	3
HNSC	TKFC →	+0.297	+0.512	<.001	<.001	3	3
LSCC	TXNDC5 →	-0.384	-0.385	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,831 associations by consensus.

ADAMTS13 vs SEC11C — LSCC

Explore this scatter interactively →