ADAMTS13

Across TCGA cell cohorts, ADAMTS13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,711 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADAMTS13-associated GO terms across cancer lineages are Cilium-dependent cell motility, Cilium or flagellum-dependent cell motility, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with ADAMTS13 in more than 16 cancer types. Because this analysis shows association rather than direction, both ADAMTS13-to-partner and partner-to-ADAMTS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium-dependent cell motility grouped by ADAMTS13-low versus ADAMTS13-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS13→partner) and Y-score (partner→ADAMTS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cilium-dependent cell motility →	-0.119	-1.918	<.001	<.001	3	17
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.119	-1.918	<.001	<.001	3	17
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.111	+1.304	<.001	<.001	3	16
LARGE_INTESTINE	Cilium movement involved in cell motility →	-0.091	-0.791	<.001	<.001	3	16
STOMACH	Regulation of myoblast fusion →	+0.137	+1.492	<.001	<.001	3	16
STOMACH	Negative regulation of myoblast fusion →	+0.122	+1.204	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,711 associations by consensus.

Cilium-dependent cell motility by ADAMTS13 expression — OESOPHAGUS

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