ADAMTS12

Across TCGA cell cohorts, ADAMTS12 RNA expression is significantly associated with the RNA expression of many other genes, with 8,423 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADAMTS12-associated genes across cancer lineages are COL8A1, DKK3, and PTX3. Each is linked with ADAMTS12 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADAMTS12-to-partner and partner-to-ADAMTS12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS12 versus COL8A1 in BONE, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS12→partner) and Y-score (partner→ADAMTS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	COL8A1 →	+4.235	+2.583	<.001	<.001	3	10
BONE	DKK3 →	+5.009	+2.594	<.001	<.001	3	10
LUNG_NSCLC_LUSC	PTX3 →	+3.314	+3.083	<.001	<.001	3	9
BONE	NEXN →	+2.912	+2.560	<.001	<.001	3	9
BREAST	FSTL1 →	+4.301	+2.585	<.001	<.001	3	9
BREAST	CAVIN1 →	+3.697	+2.203	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,423 associations by consensus.

ADAMTS12 vs COL8A1 — BONE

Explore this scatter interactively →