ADAM8

Across TCGA patient cohorts, ADAM8 RNA expression is significantly associated with the RNA expression of many other genes, with 17,938 significant associations in total. UVM shows the largest number of these associations.

The most reproducible ADAM8-associated genes across cancer lineages are HK3, THEMIS2, and OSCAR. Each is linked with ADAM8 in more than 33 cancer types. Because this analysis shows association rather than direction, both ADAM8-to-partner and partner-to-ADAM8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM8 versus HK3 in DLBC, with a Pearson correlation of 0.43.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM8→partner) and Y-score (partner→ADAM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	HK3 →	+1.788	+1.167	.001	<.001	1	34
UVM	THEMIS2 →	+1.549	+0.843	<.001	<.001	3	32
LAML	OSCAR →	+1.759	+1.187	<.001	<.001	3	31
SARC	CLEC7A →	+1.521	+1.434	<.001	<.001	3	31
SCLC	LILRB3 →	+1.164	+1.991	<.001	.002	3	31
KICH	RELB →	+1.258	+1.238	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,938 associations by consensus.

ADAM8 vs HK3 — DLBC

Explore this scatter interactively →