ADAM3B

Across TCGA patient cohorts, ADAM3B RNA expression is significantly associated with the protein abundance of many other proteins, with 8,529 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ADAM3B-associated proteins across cancer lineages are PCOLCE, TGFB3, and PRRX1. Each is linked with ADAM3B in more than 4 cancer types. Because this analysis shows association rather than direction, both ADAM3B-to-partner and partner-to-ADAM3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM3B versus PCOLCE in CCRCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM3B→partner) and Y-score (partner→ADAM3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PCOLCE →	+0.659	+0.233	<.001	<.001	3	5
UCEC	TGFB3 →	+0.603	+0.942	<.001	<.001	3	4
PDAC	PRRX1 →	+0.551	+0.349	.004	.003	3	4
PDAC	SORBS3 →	+0.325	+0.334	.002	.002	3	4
CCRCC	CNRIP1 →	+0.670	+0.455	<.001	<.001	3	4
HNSC	EPB41L2 →	+0.512	+0.700	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,529 associations by consensus.

ADAM3B vs PCOLCE — CCRCC

Explore this scatter interactively →