ADAM33

Across TCGA cell cohorts, ADAM33 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,605 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADAM33-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of cell cycle G1/S phase transition, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ADAM33 in more than 7 cancer types. Because this analysis shows association rather than direction, both ADAM33-to-partner and partner-to-ADAM33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ADAM33-low versus ADAM33-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM33→partner) and Y-score (partner→ADAM33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.083	+0.034	.004	.009	3	8
BLOOD_Leukemia	Regulation of cell cycle G1/S phase transition →	+0.053	+0.980	<.001	.003	3	7
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.081	+0.034	.004	.009	3	7
BLOOD_Lymphoma	Aromatic amino acid family catabolic process →	-0.118	-0.054	.001	.004	3	7
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.052	+0.987	<.001	.003	3	6
BLOOD_Leukemia	Regulation of stem cell population maintenance →	+0.050	+0.548	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,605 associations by consensus.

Negative regulation of myoblast fusion by ADAM33 expression — BLOOD_Lymphoma

Explore this box plot interactively →