Across TCGA patient cohorts, ADAM32 RNA expression is significantly associated with the mutation status of many other genes, with 9,725 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAM32-associated genes across cancer lineages are PREX2, TP53, and PIK3CA. Each is linked with ADAM32 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADAM32-to-partner and partner-to-ADAM32 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM32→partner) and Y-score (partner→ADAM32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PREX2 →	-4.074	-0.456	<.001	<.001	3	5
LGG	TP53 →	+0.676	+0.113	<.001	<.001	3	4
CESC	PIK3CA →	-1.351	-0.108	.002	.009	3	4
COAD	DCHS1 →	-2.489	-0.331	.001	.001	3	4
COAD	CIC →	-2.793	-0.435	.002	.001	3	3
UCEC	MTMR3 →	-1.754	-0.363	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,725 associations by consensus.

Exploration

ADAM32 survival (RNA) · tumor vs normal (RNA) · all ADAM32 data types