Across TCGA patient cohorts, ADAM32 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAM32-associated genes across cancer lineages are ATM, 4E-BP1, and eEF2. Each is linked with ADAM32 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADAM32-to-partner and partner-to-ADAM32 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM32→partner) and Y-score (partner→ADAM32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.323	-3.446	.037	.005	3	3
COAD	4E-BP1 →	+0.276	+2.178	.007	.035	3	3
UCEC	eEF2 →	+0.320	+1.514	.008	.015	3	2
UCEC	EGFR →	-0.126	-1.700	.020	.042	3	2
UCEC	A-Raf_pS299 →	-0.091	-1.514	.024	.015	3	2
UCEC	ERK2 →	+0.157	+1.874	.017	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

ADAM32 survival (RNA) · tumor vs normal (RNA) · all ADAM32 data types