Across TCGA cell cohorts, ADAM32 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADAM32-associated genes across cancer lineages are OPN1MW2, OR2B3, and FCN2. Each is linked with ADAM32 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAM32-to-partner and partner-to-ADAM32 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM32→partner) and Y-score (partner→ADAM32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OPN1MW2 →	+0.020	+5.087	<.001	.004	3	1
URINARY_TRACT	OR2B3 →	+0.020	+5.087	<.001	.004	3	1
BLOOD_Lymphoma	FCN2 →	+0.044	+3.714	<.001	.006	3	1
BLOOD_Lymphoma	OR6B1 →	+0.013	+4.058	<.001	.009	3	1
BREAST	IFNA14 →	+0.027	+4.781	<.001	.003	3	1
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ADAM32 survival (RNA) · tumor vs normal (RNA) · all ADAM32 data types