ADAM29

Across TCGA cell cohorts, ADAM29 RNA expression is significantly associated with the go_rna of many other GO terms, with 463 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ADAM29-associated GO terms across cancer lineages are Regulation of macroautophagy, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with ADAM29 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADAM29-to-partner and partner-to-ADAM29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by ADAM29-low versus ADAM29-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM29→partner) and Y-score (partner→ADAM29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of macroautophagy →	+0.036	+0.021	.001	.008	2	5
CNS	Regulation of myoblast fusion →	+0.050	+0.021	.005	.004	3	4
CNS	Negative regulation of myoblast fusion →	+0.054	+0.021	.006	.007	3	4
CNS	Regulation of syncytium formation by plasma membrane fusion →	+0.045	+0.024	.009	.004	3	4
CNS	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.049	-0.022	<.001	.003	2	5
CNS	Spermatid development →	-0.025	-0.021	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 463 associations by consensus.

Regulation of macroautophagy by ADAM29 expression — CNS

Explore this box plot interactively →