ADAM29

Across TCGA cell cohorts, ADAM29 mutation is significantly associated with the RNA expression of many other genes, with 756 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADAM29-associated genes across cancer lineages are NAF1, DESI1, and CEP76. Each is linked with ADAM29 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADAM29-to-partner and partner-to-ADAM29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NAF1 grouped by ADAM29-low versus ADAM29-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM29→partner) and Y-score (partner→ADAM29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NAF1 →	+0.537	+3.447	.005	.001	3	3
LARGE_INTESTINE	DESI1 →	+0.521	+3.169	<.001	.009	3	2
LARGE_INTESTINE	CEP76 →	+0.609	+2.502	.005	.005	3	2
LARGE_INTESTINE	TRIM37 →	+0.556	+2.502	.005	.005	3	2
LARGE_INTESTINE	SLAIN2 →	+0.608	+2.502	.003	.005	3	2
LARGE_INTESTINE	OCIAD1 →	+0.452	+3.295	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 756 associations by consensus.

NAF1 by ADAM29 expression — LARGE_INTESTINE

Explore this box plot interactively →