ADAM19

Across TCGA patient cohorts, ADAM19 protein abundance is significantly associated with the RNA expression of many other genes, with 2,439 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADAM19-associated genes across cancer lineages are SDHDP1, ELOB, and BTN1A1. Each is linked with ADAM19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAM19-to-partner and partner-to-ADAM19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM19 versus SDHDP1 in LSCC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM19→partner) and Y-score (partner→ADAM19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SDHDP1 →	-1.476	-1.179	.003	.007	3	2
LSCC	ELOB →	-0.466	-1.339	.002	.002	3	1
LSCC	BTN1A1 →	+0.218	+1.556	.001	<.001	3	1
LSCC	DEFB126 →	-1.960	-1.266	.009	<.001	3	1
LSCC	CHI3L1 →	+1.402	+1.290	.003	.001	3	1
LSCC	BCAR3 →	+1.203	+1.059	.007	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,439 associations by consensus.

ADAM19 vs SDHDP1 — LSCC

Explore this scatter interactively →