ADAM19

Across TCGA cell cohorts, ADAM19 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,027 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADAM19-associated GO terms across cancer lineages are Integrin-mediated signaling pathway, Regulation of cell-substrate adhesion, and Regulation of cell-matrix adhesion. Each is linked with ADAM19 in more than 13 cancer types. Because this analysis shows association rather than direction, both ADAM19-to-partner and partner-to-ADAM19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Integrin-mediated signaling pathway grouped by ADAM19-low versus ADAM19-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM19→partner) and Y-score (partner→ADAM19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Integrin-mediated signaling pathway →	+0.261	+2.752	<.001	<.001	3	14
BONE	Regulation of cell-substrate adhesion →	+0.120	+2.386	<.001	<.001	3	14
BONE	Regulation of cell-matrix adhesion →	+0.140	+2.146	<.001	<.001	3	14
BONE	Positive regulation of focal adhesion assembly →	+0.217	+2.192	<.001	<.001	3	13
BONE	Positive regulation of cell-substrate adhesion →	+0.138	+2.487	<.001	<.001	3	13
BONE	Regulation of protein maturation →	+0.177	+2.396	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,027 associations by consensus.

Integrin-mediated signaling pathway by ADAM19 expression — BONE

Explore this box plot interactively →