ADAM11

Across TCGA patient cohorts, ADAM11 protein abundance is significantly associated with the RNA expression of many other genes, with 3,819 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADAM11-associated genes across cancer lineages are PRODH, GRK3, and SOX10. Each is linked with ADAM11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAM11-to-partner and partner-to-ADAM11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM11 versus PRODH in GBM, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM11→partner) and Y-score (partner→ADAM11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.840	+0.403	.002	.004	3	1
GBM	GRK3 →	+0.461	+0.424	<.001	.001	3	1
GBM	SOX10 →	+1.738	+0.402	<.001	<.001	3	1
GBM	SLC16A8 →	+0.509	+0.455	.001	<.001	3	1
GBM	SUN2 →	+0.537	+0.511	<.001	<.001	3	1
GBM	RASL10A →	+1.005	+0.548	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,819 associations by consensus.

ADAM11 vs PRODH — GBM

Explore this scatter interactively →