ADAM11

Across TCGA cell cohorts, ADAM11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,065 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ADAM11-associated GO terms across cancer lineages are tRNA transcription, Constitutive heterochromatin formation, and Positive regulation of monoatomic ion transmembrane transport. Each is linked with ADAM11 in more than 14 cancer types. Because this analysis shows association rather than direction, both ADAM11-to-partner and partner-to-ADAM11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA transcription grouped by ADAM11-low versus ADAM11-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM11→partner) and Y-score (partner→ADAM11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	tRNA transcription →	+0.135	+1.337	.002	<.001	3	15
OVARY	Constitutive heterochromatin formation →	+0.079	+1.095	.001	.002	3	14
BONE	Positive regulation of monoatomic ion transmembrane transport →	-0.148	-1.375	<.001	<.001	3	13
BONE	Positive regulation of DNA metabolic process →	+0.078	+1.093	.001	.002	3	13
BONE	DNA topological change →	+0.167	+1.257	.001	<.001	3	13
STOMACH	Potassium ion import across plasma membrane →	-0.243	-1.195	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,065 associations by consensus.

tRNA transcription by ADAM11 expression — BONE

Explore this box plot interactively →