ADAD1

Across TCGA cell cohorts, ADAD1 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ADAD1-associated genes across cancer lineages are UGT2B10, WFDC10A, and KRTAP20-2. Each is linked with ADAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAD1-to-partner and partner-to-ADAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B10 grouped by ADAD1-low versus ADAD1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAD1→partner) and Y-score (partner→ADAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	UGT2B10 →	+0.133	+4.523	<.001	.003	3	1
LUNG_SCLC	WFDC10A →	+0.972	+4.817	<.001	.001	3	1
LUNG_SCLC	KRTAP20-2 →	+1.019	+4.817	<.001	.001	3	1
LUNG_SCLC	KRTAP19-2 →	+0.127	+4.643	<.001	.004	3	1
LUNG_SCLC	KRTAP19-5 →	+1.247	+4.269	<.001	.005	3	1
LUNG_SCLC	OR2J2 →	+0.040	+4.269	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

UGT2B10 by ADAD1 expression — LUNG_SCLC

Explore this box plot interactively →