ADA2

Across TCGA patient cohorts, ADA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,074 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADA2-associated proteins across cancer lineages are ANKRD44, LCP1, and ARHGAP45. Each is linked with ADA2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADA2-to-partner and partner-to-ADA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADA2 versus ANKRD44 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADA2→partner) and Y-score (partner→ADA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ANKRD44 →	+0.514	+1.137	<.001	.008	3	10
OV	LCP1 →	+0.690	+1.259	<.001	.002	2	10
GBM	ARHGAP45 →	+0.600	+1.066	<.001	<.001	3	9
GBM	SEPTIN1 →	+0.797	+0.710	.002	.003	3	9
OV	CTSS →	+0.680	+1.154	.002	.003	3	9
HNSC	EVL →	+0.734	+0.981	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,074 associations by consensus.

ADA2 vs ANKRD44 — OV

Explore this scatter interactively →