ADA2

Across TCGA cell cohorts, ADA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,812 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADA2-associated GO terms across cancer lineages are Purine nucleoside triphosphate biosynthetic process, Purine ribonucleoside triphosphate biosynthetic process, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with ADA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADA2-to-partner and partner-to-ADA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleoside triphosphate biosynthetic process grouped by ADA2-low versus ADA2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADA2→partner) and Y-score (partner→ADA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Purine nucleoside triphosphate biosynthetic process →	+0.122	+0.191	<.001	.001	3	7
OESOPHAGUS	Purine ribonucleoside triphosphate biosynthetic process →	+0.122	+0.191	<.001	.001	3	7
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.098	+1.797	.001	.009	3	7
OESOPHAGUS	Aerobic electron transport chain →	+0.094	+0.233	.001	.007	3	6
OESOPHAGUS	ATP synthesis coupled electron transport →	+0.100	+0.215	.003	.008	3	6
OESOPHAGUS	Mitochondrial ATP synthesis coupled electron transport →	+0.100	+0.215	.003	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,812 associations by consensus.

Purine nucleoside triphosphate biosynthetic process by ADA2 expression — OESOPHAGUS

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