ACVRL1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACVRL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,070 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACVRL1-associated proteins across cancer lineages are DAB2, PRKG1, and COL6A3. Each is linked with ACVRL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ACVRL1-to-partner and partner-to-ACVRL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACVRL1 versus DAB2 in GBM, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACVRL1→partner) and Y-score (partner→ACVRL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMDAB2 →+0.643+0.526<.001<.00138
OVPRKG1 →+0.665+0.769<.001<.00138
GBMCOL6A3 →+0.984+0.688<.001<.00138
CCRCCKANK3 →+0.587+0.720<.001<.00138
CCRCCFILIP1L →+0.741+0.896<.001<.00138
CCRCCOLFML1 →+1.190+0.726<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,070 associations by consensus.

ACVRL1 vs DAB2 — GBM

Per-sample scatter of ACVRL1 vs DAB2 in GBM (Pearson r = 0.37).

Explore this scatter interactively →

Exploration