ACVRL1

Across TCGA patient cohorts, ACVRL1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,240 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ACVRL1-associated genes across cancer lineages are CSF3R, ELMO3, and PWWP3A. Each is linked with ACVRL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACVRL1-to-partner and partner-to-ACVRL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACVRL1 versus CSF3R in COAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACVRL1→partner) and Y-score (partner→ACVRL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CSF3R →	+1.336	+0.336	<.001	.002	3	3
GBM	ELMO3 →	-0.546	-0.439	.006	.009	3	2
GBM	PWWP3A →	-0.601	-0.439	.005	.009	3	2
CCRCC	ZNF343 →	-0.457	-0.788	.001	.005	3	2
LSCC	PHACTR1 →	+0.532	+0.389	<.001	<.001	3	2
LSCC	ADGRL2 →	+0.562	+0.259	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,240 associations by consensus.

ACVRL1 vs CSF3R — COAD

Explore this scatter interactively →