ACVRL1

Across TCGA cell cohorts, ACVRL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,440 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACVRL1-associated GO terms across cancer lineages are Protein folding, Myotube cell development, and Negative regulation of myoblast fusion. Each is linked with ACVRL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ACVRL1-to-partner and partner-to-ACVRL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by ACVRL1-low versus ACVRL1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACVRL1→partner) and Y-score (partner→ACVRL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein folding →	+0.030	+0.854	.004	.004	3	7
OESOPHAGUS	Myotube cell development →	+0.150	+0.272	<.001	.001	3	7
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.163	+0.263	<.001	.001	3	7
OESOPHAGUS	Cytoplasmic translation →	+0.111	+0.233	<.001	.004	2	8
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.155	+0.263	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of protein localization to nucleus →	+0.072	+0.150	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,440 associations by consensus.

Protein folding by ACVRL1 expression — SOFT_TISSUE

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