ACVR1C

Across TCGA patient cohorts, ACVR1C RNA expression is significantly associated with the protein abundance of many other proteins, with 16,513 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACVR1C-associated proteins across cancer lineages are EPB41L3, CACNA2D1, and RPL22L1. Each is linked with ACVR1C in more than 3 cancer types. Because this analysis shows association rather than direction, both ACVR1C-to-partner and partner-to-ACVR1C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACVR1C versus EPB41L3 in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACVR1C→partner) and Y-score (partner→ACVR1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EPB41L3 →	+0.661	+0.717	<.001	<.001	3	4
GBM	CACNA2D1 →	+0.758	+0.622	<.001	<.001	3	4
GBM	RPL22L1 →	-0.663	-0.523	.005	.008	3	3
GBM	ATP2B4 →	+0.477	+0.800	<.001	<.001	3	3
GBM	FCHO2 →	-0.238	-0.540	<.001	<.001	3	3
LSCC	GPC1 →	+0.611	+0.605	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,513 associations by consensus.

ACVR1C vs EPB41L3 — GBM

Explore this scatter interactively →