ACVR1C

Across TCGA cell cohorts, ACVR1C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,571 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ACVR1C-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of myoblast fusion. Each is linked with ACVR1C in more than 11 cancer types. Because this analysis shows association rather than direction, both ACVR1C-to-partner and partner-to-ACVR1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ACVR1C-low versus ACVR1C-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACVR1C→partner) and Y-score (partner→ACVR1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of myoblast fusion →	+0.092	+0.452	.003	.002	3	12
BLOOD_Leukemia	Negative regulation of syncytium formation by plasma membrane fusion →	+0.080	+0.155	<.001	.006	2	12
PANCREAS	Regulation of myoblast fusion →	+0.099	+0.453	.001	.002	3	11
PANCREAS	Regulation of syncytium formation by plasma membrane fusion →	+0.082	+0.451	<.001	<.001	3	11
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.072	+0.223	.002	.007	3	10
LUNG_NSCLC_LUSC	Blastocyst growth →	-0.280	-0.935	.003	.007	1	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,571 associations by consensus.

Negative regulation of myoblast fusion by ACVR1C expression — PANCREAS

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