ACVR1C

Across TCGA cell cohorts, ACVR1C mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ACVR1C-associated genes across cancer lineages are IFNA4. Each is linked with ACVR1C in more than 1 cancer types. Because this analysis shows association rather than direction, both ACVR1C-to-partner and partner-to-ACVR1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA4 grouped by ACVR1C-low versus ACVR1C-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACVR1C→partner) and Y-score (partner→ACVR1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	IFNA4 →	+0.215	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

IFNA4 by ACVR1C expression — CNS

Explore this box plot interactively →