Across TCGA pan-cancer cohorts, ACTRT3 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ACTRT3 data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ACTRT3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ACTRT3 expression acts as an unfavorable survival marker.

HNSC are the cancer types where ACTRT3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.368	0.776	.040	4	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: ACTRT3 tumor-vs-normal RNA expression · all ACTRT3 data types