Across TCGA patient cohorts, ACTRT3 protein abundance is significantly associated with the go_rna of many other GO terms, with 5 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ACTRT3-associated GO terms across cancer lineages are Protein tetramerization, Sex differentiation, and Multicellular organismal response to stress. Each is linked with ACTRT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTRT3-to-partner and partner-to-ACTRT3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTRT3→partner) and Y-score (partner→ACTRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Protein tetramerization →	+0.063	+1.022	.006	.009	3	1
HNSC	Sex differentiation →	+0.052	+1.022	.006	.009	3	1
HNSC	Multicellular organismal response to stress →	-0.052	-0.806	.002	.005	2	1
HNSC	Cholesterol catabolic process →	-0.199	-0.960	.007	.008	2	1
HNSC	Positive regulation of muscle contraction →	-0.099	-0.806	.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

ACTRT3 survival (RNA) · tumor vs normal (RNA) · all ACTRT3 data types