Across TCGA patient cohorts, ACTRT3 mutation is significantly associated with the RNA expression of many other genes, with 407 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTRT3-associated genes across cancer lineages are RN7SL386P, CAPN5, and TMSB4Y. Each is linked with ACTRT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTRT3-to-partner and partner-to-ACTRT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTRT3→partner) and Y-score (partner→ACTRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL386P →	+0.190	+5.513	<.001	.004	3	2
UCEC	CAPN5 →	-0.840	-3.775	.001	<.001	3	1
UCEC	TMSB4Y →	+0.095	+2.370	.007	.003	3	1
UCEC	CACHD1 →	-1.030	-2.689	<.001	.006	3	1
UCEC	ZFYVE28 →	-0.553	-3.419	.002	.005	3	1
UCEC	CPAMD8 →	-1.345	-3.785	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 407 associations by consensus.

Exploration

ACTRT3 survival (RNA) · tumor vs normal (RNA) · all ACTRT3 data types