ACTRT3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACTRT3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTRT3-associated genes across cancer lineages are Platelets, pDC, and MPP. Each is linked with ACTRT3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACTRT3-to-partner and partner-to-ACTRT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTRT3→partner) and Y-score (partner→ACTRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPlatelets →+0.030+1.563<.001.04033
UCECpDC →+0.053+3.032.014.01832
LUSCMPP →+0.016+4.279<.001.00331
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

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